At our lab, we investigate how sleep turns short-lived experiences into lasting memories. While it’s known that memories move from the hippocampus to the cortex, how this transfer happens is still unclear.

We focus on the role of neural synchronization between the hippocampus (CA1) and the medial prefrontal cortex during sleep, using in vivo electrophysiology and optogenetics to track this dialogue in real time.

By decoding how sleep consolidates memory, we aim to advance our understanding of learning, aging, and disorders like PTSD and Alzheimer’s.

In our lab, sleep isn’t just rest — it’s transformation.

Beyond motor symptoms, Parkinson’s disease often involves early non-motor issues like disrupted sleep, memory loss, and psychiatric conditions—factors that greatly affect quality of life but remain poorly understood.

Using an animal model, we study how PD alters brain rhythms during sleep. We examine circadian disruptions, changes in hippocampal–thalamocortical coordination during slow-wave sleep, and REM sleep alterations. We also assess how these neural changes relate to memory deficits.

Our work links sleep disturbances to cognitive decline in PD, pointing to new biomarkers and therapeutic targets.